This document discusses various methods of fluoride therapy including systemic fluoridation and topical fluoride applications. It describes different fluoride compounds that can be used such as sodium fluoride, stannous fluoride, and acidulated phosphate fluoride. It discusses professionally applied fluoride treatments, fluoridated mouthwashes, gels, and varnishes. The document also covers the use of fluoride in periodontal therapy and lists different types of patients that may benefit from fluoride treatment.