Tasly Pharmaceutical : Breakthrough in TCM Smart Manufacture Technology (2016-07-28)

The Ministry of Industry and Information Technology has recently published the name list of Smart Manufacture Pilot Enterprises of 2016 in China. Tasly Phar. Group was selected in the list owing to its Modern TCM Smart Manufacture Project . It is reported that there are only four enterprises in pharmaceutical manufacture among the 63 approved enterprises list.

As a key composition of 'Made in China 2025' plan of the State Council, Smart Manufacture Project refers to a newly manufacturer mode based on new generation of communication technology. And it is characterized by shortening products development circle and enhancing production efficiency.

As to Modern TCM Smart Manufacture Project of Tasly Phar. Group, it showcased the advanced manufacture technology system of the international registration products of Cardiotonic Dripping Pill. This system, which has created the smart manufacture mode of modern TCM, is able to improve and promote the traditional manufacture method of TCM. Owing to this, Tasly Phar. can stand out from the rest of appraisal projects.

According to the national mid-and-long-term strategy including Made in China 2025, the 13th 5-year Plan and TCM Development Strategy Planning Outline from 2016 to 2030, Tasly has invested 150 million Yuan in this Modern TCM Smart Manufacture project. With the purpose to solve the technological bottleneck of TCM industry in production craft, manufacture equipment and online control,etc, this project has set up a digitized, intelligentized and integrated TCM smart manufacture workshop and technical system which conforms to the FDAEMA standard by creating and integrating advanced manufacture technologies such as modernized communication technology, systemic science and engineer as well as project analysis technology(PAT). In the workshop, manufacture equipment, sensor and test assembly units, data collection and the monitoring system-MES-ERP can all be connected mutually. Besides that, a whole-production- process data unified information platform and process control model database have been built which make products manufacture and management realize digitized and visibility. In 2014, the workshop won GMP Certificate approved by EU.

Owing to the effort in core equipment self-innovation and production process optimized integration, Tasly has accelerated the production pattern from quantity reproduction to continuous production. Furthermore, it has greatly enhanced the smart degree of the production equipment, production control and the management level. Therefore, while breaking through the technique bottleneck which constrain development of TCM smart production, it has made great achievements in cutting down the defect rate, enhancing production efficiency, saving production cost as well as energy saving and emission reduction.

Tasly's TCM extract enrichment equipment

Owing to TCM internationalized product R&D and break-through in industrial technologies, this project has set up a set of standardized manufacture procedure, explored a suit of digitized and modeling technologies in process control, developed a networked management system with data integration, achieved a informativeness path of enterprise management and ultimately established the intelligentized and integrated TCM manufacture and management pattern. Thus, it plays a leading role in process technology in cultivating internationalized TCM product and core competence of equipment. Besides that, Tasly had set up a modern TCM industrial chain management system, which integrate herb plant, medicine research, herbal extraction, manufacture, marketing and after-sales service all in it. This system also set up a model for TCM industry for promoting smart-manufacture technologies through upper and lower industry chain and cluster development of industrial chain supporting enterprises.

Mr. Kaijing Yan, Executive Chairman of the Board of Tasly Holding Group, has once expressed his opinion towards TCM smart manufacture in an interview. He said that: 'Under the background of Made-in-China 2025 when the government pays great attention on intelligentized development of pharmaceutical manufacture, TCM industry is facing with both opportunity and challenge resulted by industry structure adjustment which include: adopting advanced equipment, enhancing products precision, promoting production informatization and automation, accelerating production pattern from manpower to automation and intelligentization, setting up smart pharmaceutical health industrial chain, realizing green development with low energy-consumption and low pollution, realizing the strategy of sustainable development of collaboration share and mutual benefit between upstream-downstream enterprises in pharmaceutical industry, and ultimately achieve to truly industrial 4.0 era'

It is reported that Tasly has been applying one of its core products Cardiotonic Dripping Pill for FDA new drug of America. By now, it has completed all FDAⅢ clinic experiments which were carried out in 127 research centers in 9 countries and the site closure visit procedure for the pivotal phase Ⅲ trial is in progress. This project 'modern TCM smart manufacture' is based on exploration and research of Cardiotonic Dripping Pill applying for registration product of FDA. Aiming to realize TCM product structure adjustment and industrial acceleration through innovation and key technology break-through, the project has radically strengthened the market competitive advantage of modern TCM industry. Therefore, it will play great role in boosting the national strategy in building up distinguished Chinese national pharmaceutical brand and transnational enterprises with international competitiveness.

(Translated by Anna Si)