Dahonggou Creek virus, a divergent lineage of hantavirus harbored by the long-tailed mole (Scaptonyx fusicaudus)

Fig. 2

Phylogenetic tree was generated by the maximum likelihood and Bayesian methods, based on the alignment of the L-segment sequences of Dahonggou Creek virus (DHCV) strain MSB281632 (labeled in red) and other hantaviruses. Since tree topologies were very similar using RAxML and MrBayes, the tree generated by MrBayes was displayed. The phylogenetic position of DHCV (HQ616595) (labeled in red) is shown in relationship to other mole-borne hantaviruses (labeled in blue), including Asama virus (ASAV N10, EU929078), Oxbow virus (OXBV Ng1453, FJ593497), Nova virus (NVAV MSB95703, FJ593498), and Rockport virus (RKPV MSB57412, HM015221). Also shown are the phylogenetic positions of bat-borne hantaviruses, including Mouyassué virus (MOYV KB576, JQ287716), Xuan Son virus (XSV VN1982B4, JX912953), Huangpi virus (HUPV Pa-1, JX465369), Magboi virus (MGBV 1209, JN037851), Longquan virus (LQUV Ra-10, JX465379); shrew-borne hantaviruses, including Thottapalayam virus (TPMV VRC66412, EU001330), Imjin virus (MJNV Cl 05-11, EF641806), Uluguru virus (ULUV FMNH158302, JX193697), Kilimanjaro virus (KMJV FMNH174124, JX193700), Seewis virus (SWSV mp70, EF636026), Cao Bang virus (CBNV CBN-3, EF543525), Jemez Springs virus (JMSV MSB144475, FJ593501), Kenkeme virus (KKMV MSB148794, GQ306150), Amga virus (MGAV MSB148558, KM201413), Ash River virus (ARRV MSB73418, EF619961), Asikkala virus (ASIV Drahany, KC880348), Qian Hu Shan virus (QHSV YN05-284, GU566021), Tanganya virus (TGNV Tan826, EF050454), Azagny virus (AZGV KBM15, JF276228), Jeju virus (JJUV 10-11, HQ834697); and rodent-borne hantaviruses, including Hantaan virus (HTNV 76-118, NC_005222), Soochong virus (SOOV SOO-1, DQ056292), Dobrava virus (DOBV Greece, NC_005235), Seoul virus (SEOV 80-39, NC_005238), Tula virus (TULV M5302v, NC_005226), Puumala virus (PUUV Sotkamo, NC_005225), Prospect Hill virus (PHV PH-1, EF646763), Sin Nombre virus (SNV NMH10, NC_005217), and Andes virus (ANDV Chile9717869, AF291704). The numbers at each node are posterior node probabilities based on 150,000 trees. The scale bar indicates nucleotide substitutions per site