Jul 28 2015
Matinas BioPharma Holdings, Inc., a clinical-stage biopharmaceutical company focused on identifying and developing safe and effective antifungal and anti-bacterial therapeutics for the treatment of serious and life-threatening infections, today announced that preclinical data on encochleated atovaquone (CATQ) will be presented at IDWeek 2015 Oct. 7-11 in San Diego.
An oral presentation on the Company's novel lipid-crystal nano-particle delivered formulation of atovaquone entitled, "Pharmacokinetics and Efficacy of Encochleated Atovaquone (CATQ) in Murine Model of Pneumocystis," (Presentation Number 1395) is scheduled for Oct. 10, at 11:45 a.m. during the IDWeek session focused on Resistance Mechanisms.
This pre-clinical study was a collaborative effort among researchers at the National Institutes of Health (NIH), the University of Cincinnati, New Jersey School of Medicine at Rutgers University and Matinas BioPharma. The research was led by Joseph A. Kovacs, M.D., Senior Investigator with the NIH Clinical Center, and Parag Kumar, PharmD, Director of the Clinical Pharmacokinetics Research Laboratory at the NIH Clinical Center.
Atovaquone, an anti-infective agent, is currently indicated for the prevention and treatment of pneumocystis pneumonia (PCP), a condition often seen in immunocompromised patients. CATQ is formulated utilizing Matinas BioPharma's proprietary cochleate delivery technology and is currently under preclinical development in collaboration with the National Institutes of Health Clinical Center's Critical Care Medicine Department.
IDWeek 2015 abstracts will be published as an online supplement to Open Forum Infectious Diseases (OFID), the new Open Access Journal from Infectious Disease Society of America (IDSA).
Source: http://www.matinasbiopharma.com