How Effective Is Cervical Cytology Screening in Reducing Deaths From Cervical Cancer?

Diana L. Bitner, MD, NCMP

Disclosures

The North American Menopause Society (NAMS) 

In This Article

Summary

Rustagi AS, Kamineni A, Weinmann S, Reed SD, Newcomb P, Weiss NS. Cervical screening and cervical cancer death among older women: a population-based, case-control study. Am J Epidemiol. 2014;179(9):1107-1114.

Researchers in a case-control study sought to quantify the efficacy of cervical cytology screening to reduce death from cervical cancer by comparing Papanicolaou (PAP) test screening histories of women (aged 55-79 y) who died of cervical cancer between 1980 and 2010 (cases) to those of women at risk of cervical cancer (controls). Of these women, 80 eligible controls were matched 2:1 to 39 eligible cases based on health plan, age, and enrollment duration. After adjustment for matching characteristics, smoking, marital status, and race/ethnicity using logistic regression, the odds ratio of death from cervical cancer associated with screening was 0.26 (95% CI, 0.10-0.63). Researchers estimated that screening US women aged 55 to 79 years could avert 630 deaths annually.

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