The Telugu Desam Party wrested the Vijayawada Lok Sabha seat despite losing two Assembly segments to the YSRC. TDP candidate Kesineni Srinivas (Nani) won with a comfortable majority of over 80,000 votes though the YSRC won Vijayawada West and Tiruvuru Assembly segments.
The TDP candidates won the Vijayawada East and Central, Mylavaram, Nandigama and Jaggaiahpet segments. TDP district president Devineni Uma Maheswara Rao defeated his YSRC rival and former MLA Jogi Ramesh with a margin of 6,050 votes. TDP candidate Sriram Rajasekhar (Thataiah) defeated formidable rival and former government whip Samineni Udayabhanu.